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This slows or stops the movement of food through the stomach without any physical blockage
Although DPP-4 inhibitors are now common in clinical practice, they increase active GLP-1 levels only to a modest degree, and are not specific to GLP-1
Mounting evidence demonstrates their efficacy in reducing cardiovascular and renal risk, improving hepatic outcomes, and potentially modulating neurological and inflammatory pathways
Tirzepatides Phase 3 programme is four years deeper, its three FDA approvals span type 2 diabetes, chronic weight management and obstructive sleep apnoea, and its published cardiovascular outcomes trial in more than thirteen thousand patients is a fact we do not dispute 12 28
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